Which form of vitamin B12 is the most absorbable?

Many people take additional vitamin B12, particularly vegetarians and vegans. They are at a higher risk of developing a deficiency since B12 is primarily found in animal products. If you are taking vitamin B12, it may be useful to know which form is most absorbable, and we've outlined this for you below.

Vitamin B12 Supplements

B12 with Cyanocobalamin

Most B12 supplements contain cyanocobalamin. This form does not naturally occur in living organisms but has the advantage of being very stable. However, this stability has a downside. To be used by the body, the cyano part must first be removed, and then the cobalamin must be converted into the active forms of vitamin B12: methylcobalamin and adenosylcobalamin. These steps are not always efficient, especially in older people, those with stomach issues, or those using antacids.

Active Vitamin B12

There is clear evidence that taking an active vitamin B12, such as methylcobalamin, is preferable to taking cyanocobalamin. Methylcobalamin is better retained by the tissues than cyanocobalamin. This does not mean cyanocobalamin is not absorbed or has no effect at all. It just takes longer to achieve the desired result.

You can find supplements with methylcobalamin here

Author: Sanne van der Rijt