In all Vitals products containing vitamin B6, only pyridoxal-5’-phosphate (P-5’-P) is used, the biologically active form of vitamin B6, and not pyridoxine-HCL which needs to be converted in the body. Vitamin B6 in its biologically active form of pyridoxal-5’-phosphate acts as a co-factor in more than 140 enzymatic reactions in the body and thus has various physiological functions. For instance, nearly all amino acids require one or more enzymes dependent on pyridoxal-5’-phosphate for their metabolism. P-5’-P dependent enzymes also play a role in glycogen metabolism. In this way, vitamin B6 contributes to good energy provision and can help with fatigue.

Pyridoxal-5’-phosphate is also involved in the production of haem compounds and haemoglobin, ensuring that more oxygen can be bound to and released from red blood cells. Haem compounds are also present in mitochondria, which further explains the contribution of pyridoxal-5’-phosphate to energy levels. Since pyridoxal-5’-phosphate is also absorbed in the brain and P-5’-P dependent enzymes play a role in the production of neurotransmitters, it also contributes to normal brain and nerve functions.

Vitamin B6 also plays a role in the immune system as it is needed as a co-enzyme for the production of certain immunoglobulins (antibodies produced to neutralise viruses or bacteria) and cytokines (substances that send signals to activate or inhibit the immune system). Additionally, it contributes to the production of cysteine and the production and breakdown of homocysteine. Finally, vitamin B6 helps regulate hormone activity.

Safe upper limit

High dosages of vitamin B6 can occasionally lead to tingling or numbness in the hands or feet. Therefore, in the Netherlands, a maximum safe upper limit of 21 mg per day for adults is applied for vitamin supplements. Research is being conducted to determine whether these occasional cases only occur with vitamin B6 in the form of pyridoxine-HCL and not, or to a lesser extent, with pyridoxal-5’-phosphate. There are indications that only pyridoxine in high dosages is toxic to nerve cells, and not P-5’-P.

Vitamin B6 pyridoxal-5’-phosphate 20 mg from Vitals offers a generous dosage in pure, biologically active form. The raw material is contained in a plant-based capsule made from cassava and is supplemented with an excipient from rice.

Other information

EAN: (100 Plant-based capsules) 8716717003358

Composition per capsule: (daily dosage) %RI*
Vitamin B6 (pyridoxal-5'-phosphate) 20 mg 1429%

* RI = Reference Intake

Ingredients:
Anti-caking agent: rice concentrate, vegetarian capsule: pullulan (from fermented cassava starch), pyridoxal-5’-phosphate (P-5’-P).

Does not contain:
Gluten, lactose, soy, GMO, preservatives and synthetic fragrances, colours, and flavours.

Suitable for vegetarians and vegans.

Take 1 capsule daily with a meal with water, or as advised.

This dietary supplement is not suitable for children up to and including 17 years of age (legally required statement for products with more than 7 mg of vitamin B6 per daily dosage).

In rare cases, vitamin B6 can cause mild tingling or numbness in limbs. Discontinue use of the product if you experience this.

This product is a dietary supplement (Vitamin preparation).

Adhere to the recommended dosage.

A varied, balanced diet and a healthy lifestyle are important.

A dietary supplement is not a substitute for a varied diet.

Keep out of reach of young children.

Store in a dry, sealed place at room temperature, unless otherwise advised on the label.

Consult an expert before using supplements in case of pregnancy, lactation, medication use, and illness.

Vitamin B6