Mucuna Pruriens can, if necessary, be used throughout the year, without interruptions and for as long as you wish.

Yes, Mucuna Pruriens can be safely combined with Crocus sativus extract.

There are no known interactions between Mucuna Pruriens and SSRI antidepressants. However, combining it with MAO inhibitors is not recommended.

Tapering off medication should always be done in consultation with the treating physician. Mucuna Pruriens cannot be compared in effect to a medicinal MAOi or SSRI (or herbs such as St. John's Wort). But if your doctor approves reducing your medication, you can see how Mucuna Pruriens affects you.

Yes, Mucuna Pruriens 0833 /B combines well with St. John's Wort.

Whether an herb or dietary supplement can replace antidepressants depends on the severity of the situation. Nowadays, antidepressants are widely prescribed, even to people who are not actually depressed. In many of those cases, there are perfectly good alternatives. Even with mild depression, one can certainly opt for a natural alternative. In this regard, St. John's Wort is particularly known as an effective remedy, but I assume you are already familiar with it and are consciously looking for another option.

Mucuna Pruriens 0833 /B is suitable for both men and women. Although it does not enjoy the same reputation as St. John's Wort, the manufacturer does state that "the legumes of this plant are rich in substances that promote happiness, pleasure, and motivation." This refers to L-dopa, serotonin, and 5-HTP.

So it is worth trying. Preferably in consultation with your doctor.